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Human DJ-1-specific Transcriptional Activation of Tyrosine Hydroxylase Gene
Loss-of-function mutation in the DJ-1 gene causes a subset of familial Parkinson disease. The mechanism underlying DJ-1-related selective vulnerability in the dopaminergic pathway is, however, not known. DJ-1 has multiple functions, including transcriptional regulation, and one of transcriptional ta...
Autores principales: | Ishikawa, Shizuma, Taira, Takahiro, Takahashi-Niki, Kazuko, Niki, Takeshi, Ariga, Hiroyoshi, Iguchi-Ariga, Sanae M. M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000953/ https://www.ncbi.nlm.nih.gov/pubmed/20938049 http://dx.doi.org/10.1074/jbc.M110.137034 |
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