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Inactivation of Adenosine A(2A) Receptor Attenuates Basal and Angiotensin II-induced ROS Production by Nox2 in Endothelial Cells

Endothelial cells (ECs) express a Nox2 enzyme, which, by generating reactive oxygen species (ROS), contributes to EC redox signaling and angiotensin II (AngII)-induced endothelial dysfunction. ECs also express abundantly an adenosine A(2A) receptor (A(2A)R), but its role in EC ROS production remains...

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Detalles Bibliográficos
Autores principales:	Thakur, Sapna, Du, Junjie, Hourani, Susanna, Ledent, Catherine, Li, Jian-Mei
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2010
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000993/ https://www.ncbi.nlm.nih.gov/pubmed/20940302 http://dx.doi.org/10.1074/jbc.M110.184606

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