Gradient of Increasing Aurora B Kinase Activity Is Required for Cells to Execute Mitosis

INCENP, Borealin, Survivin, and Aurora B kinase comprise the chromosomal passenger complex, an essential regulator of mitotic events. INCENP (inner centromere protein) binds and activates Aurora B through a feedback loop involving phosphorylation of a Thr-Ser-Ser (TSS) motif near the INCENP C termin...

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Detalles Bibliográficos
Autores principales: Xu, Zhenjie, Vagnarelli, Paola, Ogawa, Hiromi, Samejima, Kumiko, Earnshaw, William C.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000998/
https://www.ncbi.nlm.nih.gov/pubmed/20956539
http://dx.doi.org/10.1074/jbc.M110.181545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000998/
https://www.ncbi.nlm.nih.gov/pubmed/20956539
http://dx.doi.org/10.1074/jbc.M110.181545

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