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Gradient of Increasing Aurora B Kinase Activity Is Required for Cells to Execute Mitosis

INCENP, Borealin, Survivin, and Aurora B kinase comprise the chromosomal passenger complex, an essential regulator of mitotic events. INCENP (inner centromere protein) binds and activates Aurora B through a feedback loop involving phosphorylation of a Thr-Ser-Ser (TSS) motif near the INCENP C termin...

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Detalles Bibliográficos
Autores principales:	Xu, Zhenjie, Vagnarelli, Paola, Ogawa, Hiromi, Samejima, Kumiko, Earnshaw, William C.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2010
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000998/ https://www.ncbi.nlm.nih.gov/pubmed/20956539 http://dx.doi.org/10.1074/jbc.M110.181545

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