Vibrio cholerae ParE2 Poisons DNA Gyrase via a Mechanism Distinct from Other Gyrase Inhibitors

DNA gyrase is an essential bacterial enzyme required for the maintenance of chromosomal DNA topology. This enzyme is the target of several protein toxins encoded in toxin-antitoxin (TA) loci as well as of man-made antibiotics such as quinolones. The genome of Vibrio cholerae, the cause of cholera, c...

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Detalles Bibliográficos
Autores principales: Yuan, Jie, Sterckx, Yann, Mitchenall, Lesley A., Maxwell, Anthony, Loris, Remy, Waldor, Matthew K.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
DNA and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001019/
https://www.ncbi.nlm.nih.gov/pubmed/20952390
http://dx.doi.org/10.1074/jbc.M110.138776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001019/
https://www.ncbi.nlm.nih.gov/pubmed/20952390
http://dx.doi.org/10.1074/jbc.M110.138776

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