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ChIPing the cistrome of PXR in mouse liver

The pregnane X receptor (PXR) is a key regulator of xenobiotic metabolism and disposition in liver. However, little is known about the PXR DNA-binding signatures in vivo, or how PXR regulates novel direct targets on a genome-wide scale. Therefore, we generated a roadmap of hepatic PXR bindings in th...

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Detalles Bibliográficos
Autores principales:	Cui, Julia Yue, Gunewardena, Sumedha S., Rockwell, Cheryl E., Klaassen, Curtis D.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001051/ https://www.ncbi.nlm.nih.gov/pubmed/20693526 http://dx.doi.org/10.1093/nar/gkq654

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