Genomics of human longevity

In animal models, single-gene mutations in genes involved in insulin/IGF and target of rapamycin signalling pathways extend lifespan to a considerable extent. The genetic, genomic and epigenetic influences on human longevity are expected to be much more complex. Strikingly however, beneficial metabo...

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Detalles Bibliográficos
Autores principales: Slagboom, P. E., Beekman, M., Passtoors, W. M., Deelen, J., Vaarhorst, A. A. M., Boer, J. M., van den Akker, E. B., van Heemst, D., de Craen, A. J. M., Maier, A. B., Rozing, M., Mooijaart, S. P., Heijmans, B. T., Westendorp, R. G. J.
Formato: Texto
Lenguaje:English
Publicado: The Royal Society 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001312/
https://www.ncbi.nlm.nih.gov/pubmed/21115528
http://dx.doi.org/10.1098/rstb.2010.0284

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