How the vertebrates were made: selective pruning of a double-duplicated genome

Vertebrates are the result of an ancient double duplication of the genome. A new study published in BMC Biology explores the selective retention of genes after this event, finding an extensive enrichment of signaling proteins and transcription factors. Analysis of their expression patterns, interact...

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Detalles Bibliográficos
Autores principales: Manning, Gerard, Scheeff, Eric
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001425/
https://www.ncbi.nlm.nih.gov/pubmed/21144066
http://dx.doi.org/10.1186/1741-7007-8-144
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author Manning, Gerard
Scheeff, Eric
author_facet Manning, Gerard
Scheeff, Eric
author_sort Manning, Gerard
collection PubMed
description Vertebrates are the result of an ancient double duplication of the genome. A new study published in BMC Biology explores the selective retention of genes after this event, finding an extensive enrichment of signaling proteins and transcription factors. Analysis of their expression patterns, interactions and subsequent history reflect the forces that drove their evolution, and with it the evolution of vertebrate complexity. See research article: http://www.biomedcentral.com/1741-7007/8/146/abstract
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spelling pubmed-30014252010-12-15 How the vertebrates were made: selective pruning of a double-duplicated genome Manning, Gerard Scheeff, Eric BMC Biol Commentary Vertebrates are the result of an ancient double duplication of the genome. A new study published in BMC Biology explores the selective retention of genes after this event, finding an extensive enrichment of signaling proteins and transcription factors. Analysis of their expression patterns, interactions and subsequent history reflect the forces that drove their evolution, and with it the evolution of vertebrate complexity. See research article: http://www.biomedcentral.com/1741-7007/8/146/abstract BioMed Central 2010-12-13 /pmc/articles/PMC3001425/ /pubmed/21144066 http://dx.doi.org/10.1186/1741-7007-8-144 Text en Copyright ©2010 Manning and Scheeff; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (<url>http://creativecommons.org/licenses/by/2.0</url>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Manning, Gerard
Scheeff, Eric
How the vertebrates were made: selective pruning of a double-duplicated genome
title How the vertebrates were made: selective pruning of a double-duplicated genome
title_full How the vertebrates were made: selective pruning of a double-duplicated genome
title_fullStr How the vertebrates were made: selective pruning of a double-duplicated genome
title_full_unstemmed How the vertebrates were made: selective pruning of a double-duplicated genome
title_short How the vertebrates were made: selective pruning of a double-duplicated genome
title_sort how the vertebrates were made: selective pruning of a double-duplicated genome
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001425/
https://www.ncbi.nlm.nih.gov/pubmed/21144066
http://dx.doi.org/10.1186/1741-7007-8-144
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