Induction of Heme Oxygenase-1 Can Halt and Even Reverse Renal Tubule-Interstitial Fibrosis

BACKGROUND: The tubule-interstitial fibrosis is the hallmark of progressive renal disease and is strongly associated with inflammation of this compartment. Heme-oxygenase-1 (HO-1) is a cytoprotective molecule that has been shown to be beneficial in various models of renal injury. However, the role o...

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Detalles Bibliográficos
Autores principales: Correa-Costa, Matheus, Semedo, Patricia, Monteiro, Ana Paula F. S., Silva, Reinaldo C., Pereira, Rafael L., Gonçalves, Giselle M., Marques, Georgia Daniela Marcusso, Cenedeze, Marcos A., Faleiros, Ana C. G., Keller, Alexandre C., Shimizu, Maria H. M., Seguro, Antônio C., Reis, Marlene A., Pacheco-Silva, Alvaro, Câmara, Niels O. S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001459/
https://www.ncbi.nlm.nih.gov/pubmed/21179206
http://dx.doi.org/10.1371/journal.pone.0014298

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