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Receptor-Mediated Enhancement of Beta Adrenergic Drug Activity by Ascorbate In Vitro and In Vivo

RATIONALE: Previous in vitro research demonstrated that ascorbate enhances potency and duration of activity of agonists binding to alpha 1 adrenergic and histamine receptors. OBJECTIVES: Extending this work to beta 2 adrenergic systems in vitro and in vivo. METHODS: Ultraviolet spectroscopy was used...

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Detalles Bibliográficos
Autores principales: Dillon, Patrick F., Root-Bernstein, Robert, Robinson, N. Edward, Abraham, William M., Berney, Catherine
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001466/
https://www.ncbi.nlm.nih.gov/pubmed/21179213
http://dx.doi.org/10.1371/journal.pone.0015130