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Surface Phenotype and Functionality of WNV Specific T Cells Differ with Age and Disease Severity
West Nile virus (WNV) infection can result in severe neuroinvasive disease, particularly in persons with advanced age. As rodent models demonstrate that T cells play an important role in limiting WNV infection, and strong T cell responses to WNV have been observed in humans, we postulated that inade...
Autores principales: | Piazza, Paolo, McMurtrey, Curtis P., Lelic, Alina, Cook, Robert L., Hess, Rachel, Yablonsky, Eric, Borowski, Luann, Loeb, Mark B., Bramson, Jonathan L., Hildebrand, William H., Rinaldo, Charles R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001480/ https://www.ncbi.nlm.nih.gov/pubmed/21179445 http://dx.doi.org/10.1371/journal.pone.0015343 |
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