The Neurotoxicity of DOPAL: Behavioral and Stereological Evidence for Its Role in Parkinson Disease Pathogenesis

BACKGROUND: The etiology of Parkinson disease (PD) has yet to be fully elucidated. We examined the consequences of injections of 3,4-dihydroxyphenylacetaldehyde (DOPAL), a toxic metabolite of dopamine, into the substantia nigra of rats on motor behavior and neuronal survival. METHODS/PRINCIPAL FINDI...

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Detalles Bibliográficos
Autores principales: Panneton, W. Michael, Kumar, V. B., Gan, Qi, Burke, William J., Galvin, James E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001493/
https://www.ncbi.nlm.nih.gov/pubmed/21179455
http://dx.doi.org/10.1371/journal.pone.0015251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001493/
https://www.ncbi.nlm.nih.gov/pubmed/21179455
http://dx.doi.org/10.1371/journal.pone.0015251

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