Increased prevalence of the pfdhfr/phdhps quintuple mutant and rapid emergence of pfdhps resistance mutations at codons 581 and 613 in Kisumu, Kenya

BACKGROUND: Anti-malarial drug resistance in Kenya prompted two drug policy changes within a decade: sulphadoxine-pyrimethamine (SP) replaced chloroquine (CQ) as the first-line anti-malarial in 1998 and artemether-lumefantrine (AL) replaced SP in 2004. Two cross-sectional studies were conducted to m...

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Detalles Bibliográficos
Autores principales: Spalding, Maroya D, Eyase, Fredrick L, Akala, Hoseah M, Bedno, Sheryl A, Prigge, Sean T, Coldren, Rodney L, Moss, William J, Waters, Norman C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001743/
https://www.ncbi.nlm.nih.gov/pubmed/21106088
http://dx.doi.org/10.1186/1475-2875-9-338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001743/
https://www.ncbi.nlm.nih.gov/pubmed/21106088
http://dx.doi.org/10.1186/1475-2875-9-338

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