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Transcriptional Activation of REST by Sp1 in Huntington's Disease Models

In Huntington's disease (HD), mutant huntingtin (mHtt) disrupts the normal transcriptional program of disease neurons by altering the function of several gene expression regulators such as Sp1. REST (Repressor Element-1 Silencing Transcription Factor), a key regulator of neuronal differentiatio...

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Detalles Bibliográficos
Autores principales:	Ravache, Myriam, Weber, Chantal, Mérienne, Karine, Trottier, Yvon
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001865/ https://www.ncbi.nlm.nih.gov/pubmed/21179468 http://dx.doi.org/10.1371/journal.pone.0014311

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