Cargando…

Profiling of VEGFs and VEGFRs as Prognostic Factors in Soft Tissue Sarcoma: VEGFR-3 Is an Independent Predictor of Poor Prognosis

BACKGROUND: In non-gastrointestinal stromal tumor soft tissue sarcoma (non-GIST STS) optimal treatment is surgery with wide resection margins. Vascular endothelial growth factors (VEGFs) and receptors (VEGFRs) are known to be key players in the initiation of angiogenesis and lymphangiogenesis. This...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kilvaer, Thomas K., Valkov, Andrej, Sorbye, Sveinung, Smeland, Eivind, Bremnes, Roy M., Busund, Lill-Tove, Donnem, Tom
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001883/ https://www.ncbi.nlm.nih.gov/pubmed/21179485 http://dx.doi.org/10.1371/journal.pone.0015368

Ejemplares similares

The VEGF- and PDGF-family of angiogenic markers have prognostic impact in soft tissue sarcomas arising in the extremities and trunk
por: Kilvaer, Thomas K, et al.
Publicado: (2014)

Platelet-Derived Growth Factors in Non-GIST Soft-Tissue Sarcomas Identify a Subgroup of Patients with Wide Resection Margins and Poor Disease-Specific Survival
por: Kilvaer, Thomas Karsten, et al.
Publicado: (2010)

Prognostic Impacts of Hypoxic Markers in Soft Tissue Sarcoma
por: Smeland, Eivind, et al.
Publicado: (2012)

Prognostic Impact of Lymphocytes in Soft Tissue Sarcomas
por: Sorbye, Sveinung W., et al.
Publicado: (2011)

The Prognostic Impact of TGF-β1, Fascin, NF-κB and PKC-ζ Expression in Soft Tissue Sarcomas
por: Valkov, Andrej, et al.
Publicado: (2011)

The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas
por: Valkov, Andrej, et al.
Publicado: (2011)

Prognostic impact of peritumoral lymphocyte infiltration in soft tissue sarcomas
por: Sorbye, Sveinung W, et al.
Publicado: (2012)

Prognostic impact of Skp2, ER and PGR in male and female patients with soft tissue sarcomas
por: Sorbye, Sveinung W, et al.
Publicado: (2013)

Prognostic Impact of Jab1, p16, p21, p62, Ki67 and Skp2 in Soft Tissue Sarcomas
por: Sorbye, Sveinung W., et al.
Publicado: (2012)

Prognostic impact of CD57, CD68, M-CSF, CSF-1R, Ki67 and TGF-beta in soft tissue sarcomas
por: Sorbye, Sveinung W, et al.
Publicado: (2012)

Fibroblast growth factor 2 orchestrates angiogenic networking in non-GIST STS patients
por: Kilvaer, Thomas K, et al.
Publicado: (2011)

High tumor cell expression of microRNA-21 in node positive non-small cell lung cancer predicts a favorable clinical outcome
por: Stenvold, Helge, et al.
Publicado: (2014)

Lymphangiogenic Markers and Their Impact on Nodal Metastasis and Survival in Non-Small Cell Lung Cancer - A Structured Review with Meta-Analysis
por: Kilvaer, Thomas K., et al.
Publicado: (2015)

Digitally quantified CD8(+) cells: the best candidate marker for an immune cell score in non-small cell lung cancer?
por: Kilvaer, Thomas K, et al.
Publicado: (2020)

Prognostic Impacts of Angiopoietins in NSCLC Tumor Cells and Stroma: VEGF-A Impact Is Strongly Associated with Ang-2
por: Andersen, Sigve, et al.
Publicado: (2011)

The impact of MET, IGF-1, IGF1R expression and EGFR mutations on survival of patients with non-small-cell lung cancer
por: Al-Saad, Samer, et al.
Publicado: (2017)

The presence of intraepithelial CD45RO+ cells in resected lymph nodes with metastases from NSCLC patients is an independent predictor of disease-specific survival
por: Kilvaer, Thomas K, et al.
Publicado: (2016)

Prognostic Impact of MiR-155 in Non-Small Cell Lung Cancer Evaluated by in Situ Hybridization
por: Donnem, Tom, et al.
Publicado: (2011)

Tissue analyses reveal a potential immune-adjuvant function of FAP-1 positive fibroblasts in non-small cell lung cancer
por: Kilvaer, Thomas Karsten, et al.
Publicado: (2018)

High expression of microRNA-126 relates to favorable prognosis for colon cancer patients
por: Selven, Hallgeir, et al.
Publicado: (2021)

CTLA-4 expression in the non-small cell lung cancer patient tumor microenvironment: diverging prognostic impact in primary tumors and lymph node metastases
por: Paulsen, Erna-Elise, et al.
Publicado: (2017)

Prognostic effect of intratumoral neutrophils across histological subtypes of non-small cell lung cancer
por: Rakaee, Mehrdad, et al.
Publicado: (2016)

VEGF-VEGFR Signals in Health and Disease
por: Shibuya, Masabumi
Publicado: (2014)

Diagnostic Value of VEGF-A, VEGFR-1 and VEGFR-2 in Feline Mammary Carcinoma
por: Nascimento, Catarina, et al.
Publicado: (2021)

The prognostic role of immune checkpoint markers programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) in a large, multicenter prostate cancer cohort
por: Ness, Nora, et al.
Publicado: (2017)

Stage and tissue-specific prognostic impact of miR-182 in NSCLC
por: Stenvold, Helge, et al.
Publicado: (2014)

Cancer Associated Fibroblasts in Stage I-IIIA NSCLC: Prognostic Impact and Their Correlations with Tumor Molecular Markers
por: Kilvaer, Thomas K., et al.
Publicado: (2015)

Stromal Expression of MiR-21 Predicts Biochemical Failure in Prostate Cancer Patients with Gleason Score 6
por: Melbø-Jørgensen, Christian, et al.
Publicado: (2014)

Fibroblast miR-210 overexpression is independently associated with clinical failure in Prostate Cancer – a multicenter (in situ hybridization) study
por: Andersen, Sigve, et al.
Publicado: (2016)

Rapamycin suppresses angiogenesis and lymphangiogenesis in melanoma by downregulating VEGF-A/VEGFR-2 and VEGF-C/VEGFR-3 expression
por: Wang, Min, et al.
Publicado: (2019)

Changes in the Expression Profile of VEGF-A, VEGF-B, VEGFR-1, VEGFR-2 in Different Grades of Endometrial Cancer
por: Dziobek, Konrad, et al.
Publicado: (2019)

VEGF-dependent tumor angiogenesis requires the inverse and reciprocal regulation of VEGFR1 and VEGFR2
por: Zhang, Zhaocheng, et al.
Publicado: (2009)

Prognostic Value of Macrophage Phenotypes in Resectable Non–Small Cell Lung Cancer Assessed by Multiplex Immunohistochemistry()
por: Rakaee, Mehrdad, et al.
Publicado: (2019)

High expression of PDGFR-β in prostate cancer stroma is independently associated with clinical and biochemical prostate cancer recurrence
por: Nordby, Yngve, et al.
Publicado: (2017)

Targeting VEGF/VEGFR to Modulate Antitumor Immunity
por: Yang, Ju, et al.
Publicado: (2018)

A gender specific improved survival related to stromal miR-143 and miR-145 expression in non-small cell lung cancer
por: Skjefstad, Kaja, et al.
Publicado: (2018)

Effects of oestradiol and tamoxifen on VEGF, soluble VEGFR-1, and VEGFR-2 in breast cancer and endothelial cells
por: Garvin, S, et al.
Publicado: (2005)

Overexpression of the HIF Hydroxylases PHD1, PHD2, PHD3 and FIH Are Individually and Collectively Unfavorable Prognosticators for NSCLC Survival
por: Andersen, Sigve, et al.
Publicado: (2011)

Association between intratumoral free and total VEGF, soluble VEGFR-1, VEGFR-2 and prognosis in breast cancer
por: Bando, H, et al.
Publicado: (2005)

Genetic variations in VEGF and VEGFR2 and glioblastoma outcome
por: Sjöström, S., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_64m85b8pigs4n822u2heo9ocsu