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Metabolic Activity and mRNA Levels of Human Cardiac CYP450s Involved in Drug Metabolism
BACKGROUND: Tissue-specific expression of CYP450s can regulate the intracellular concentration of drugs and explain inter-subject variability in drug action. The overall objective of our study was to determine in a large cohort of samples, mRNA levels and CYP450 activity expressed in the human heart...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001885/ https://www.ncbi.nlm.nih.gov/pubmed/21179487 http://dx.doi.org/10.1371/journal.pone.0015666 |