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Antibiotic Selection Pressure and Macrolide Resistance in Nasopharyngeal Streptococcus pneumoniae: A Cluster-Randomized Clinical Trial

BACKGROUND: It is widely thought that widespread antibiotic use selects for community antibiotic resistance, though this has been difficult to prove in the setting of a community-randomized clinical trial. In this study, we used a randomized clinical trial design to assess whether macrolide resistan...

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Detalles Bibliográficos
Autores principales: Skalet, Alison H., Cevallos, Vicky, Ayele, Berhan, Gebre, Teshome, Zhou, Zhaoxia, Jorgensen, James H., Zerihun, Mulat, Habte, Dereje, Assefa, Yared, Emerson, Paul M., Gaynor, Bruce D., Porco, Travis C., Lietman, Thomas M., Keenan, Jeremy D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001893/
https://www.ncbi.nlm.nih.gov/pubmed/21179434
http://dx.doi.org/10.1371/journal.pmed.1000377