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Chemoprevention of Nonmelanoma Skin Cancer With Celecoxib: A Randomized, Double-Blind, Placebo-Controlled Trial
BACKGROUND: Preclinical studies indicate that the enzyme cyclooxygenase 2 plays an important role in ultraviolet-induced skin cancers. We evaluated the efficacy and safety of celecoxib, a cyclooxygenase 2 inhibitor, as a chemopreventive agent for actinic keratoses, the premalignant precursor of nonm...
Autores principales: | Elmets, Craig A., Viner, Jaye L., Pentland, Alice P., Cantrell, Wendy, Lin, Hui-Yi, Bailey, Howard, Kang, Sewon, Linden, Kenneth G., Heffernan, Michael, Duvic, Madeleine, Richmond, Ellen, Elewski, Boni E., Umar, Asad, Bell, Walter, Gordon, Gary B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001966/ https://www.ncbi.nlm.nih.gov/pubmed/21115882 http://dx.doi.org/10.1093/jnci/djq442 |
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