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Dynamic macrophage “probing” is required for the efficient capture of phagocytic targets

Binding of ligands by immunoreceptors is thought to be a passive, stochastic process. Contrary to this notion, we found that binding of IgG-opsonized particles by Fcγ receptors was inhibited in macrophages, dendritic and microglial cells by agents that interfere with actin assembly or disassembly. C...

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Detalles Bibliográficos
Autores principales: Flannagan, Ronald S., Harrison, Rene E., Yip, Christopher M., Jaqaman, Khuloud, Grinstein, Sergio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002038/
https://www.ncbi.nlm.nih.gov/pubmed/21135140
http://dx.doi.org/10.1083/jcb.201007056