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Melatonin Alters Age-Related Changes in Transcription Factors and Kinase Activation
Male mice were fed 40 ppm melatonin for 2 months prior to sacrifice at age 26 months, and compared with both 26 and 4 month-old untreated controls. The nuclear translocation of NF-κB increased with age in both brain and spleen and this was reversed by melatonin only in brain. Another transcription f...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002167/ https://www.ncbi.nlm.nih.gov/pubmed/20535557 http://dx.doi.org/10.1007/s11064-010-0206-3 |