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Population Genetic Analysis of the Uncoupling Proteins Supports a Role for UCP3 in Human Cold Resistance

Production of heat via nonshivering thermogenesis (NST) is critical for temperature homeostasis in mammals. Uncoupling protein UCP1 plays a central role in NST by uncoupling the proton gradients produced in the inner membranes of mitochondria to produce heat; however, the extent to which UCP1 homolo...

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Detalles Bibliográficos
Autores principales:	Hancock, Angela M., Clark, Vanessa J., Qian, Yudong, Di Rienzo, Anna
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002247/ https://www.ncbi.nlm.nih.gov/pubmed/20802238 http://dx.doi.org/10.1093/molbev/msq228

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