A Novel Dimeric Inhibitor Targeting Beta2GPI in Beta2GPI/Antibody Complexes Implicated in Antiphospholipid Syndrome

BACKGROUND: β2GPI is a major antigen for autoantibodies associated with antiphospholipid syndrome (APS), an autoimmune disease characterized by thrombosis and recurrent pregnancy loss. Only the dimeric form of β2GPI generated by anti-β2GPI antibodies is pathologically important, in contrast to monom...

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Detalles Bibliográficos
Autores principales: Kolyada, Alexey, Lee, Chang-Jin, De Biasio, Alfredo, Beglova, Natalia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002267/
https://www.ncbi.nlm.nih.gov/pubmed/21179511
http://dx.doi.org/10.1371/journal.pone.0015345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002267/
https://www.ncbi.nlm.nih.gov/pubmed/21179511
http://dx.doi.org/10.1371/journal.pone.0015345

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