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Genetic Variants in Toll-Like Receptors Are Not Associated with Rheumatoid Arthritis Susceptibility or Anti-Tumour Necrosis Factor Treatment Outcome

BACKGROUND: Several studies point to a role of Toll-like receptors (TLRs) in the development of rheumatoid arthritis (RA). We investigated if genetic variants in TLR genes are associated with RA and response to tumour necrosis factor blocking (anti-TNF) medication. METHODOLOGY AND PRINCIPAL FINDINGS...

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Detalles Bibliográficos
Autores principales:	Coenen, Marieke J. H., Enevold, Christian, Barrera, Pilar, Schijvenaars, Mascha M. V. A. P., Toonen, Erik J. M., Scheffer, Hans, Padyukov, Leonid, Kastbom, Alf, Klareskog, Lars, Barton, Anne, Kievit, Wietske, Rood, Maarten J., Jansen, Tim L., Swinkels, Dorine, van Riel, Piet L. C. M., Franke, Barbara, Bendtzen, Klaus, Radstake, Timothy R. D. J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002281/ https://www.ncbi.nlm.nih.gov/pubmed/21179534 http://dx.doi.org/10.1371/journal.pone.0014326

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