NSP2 gene variation of the North American genotype of the Thai PRRSV in central Thailand

Porcine reproductive and respiratory syndrome virus (PRRSV) is a major swine pathogen causing economic losses in the swine industry almost worldwide. PRRSV has been divided into 2 genotypes, the European (Type 1) and North American (Type 2) genotype, respectively and displays a large degree of genet...

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Detalles Bibliográficos
Autores principales: Kedkovid, Roongtham, Nuntawan Na Ayudhya, Suparlark, Amonsin, Alongkorn, Thanawongnuwech, Roongroje
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002309/
https://www.ncbi.nlm.nih.gov/pubmed/21092327
http://dx.doi.org/10.1186/1743-422X-7-340
Descripción
Sumario:Porcine reproductive and respiratory syndrome virus (PRRSV) is a major swine pathogen causing economic losses in the swine industry almost worldwide. PRRSV has been divided into 2 genotypes, the European (Type 1) and North American (Type 2) genotype, respectively and displays a large degree of genetic variability, particularly at the nonstructural protein (nsp) 2 gene. This is the first study determining genetic variation of the nsp2 of Thai PRRSV isolates. The results showed that 9 out of 10 Thai PRRSV isolates were nsp2-truncated viruses that might have evolved from a virus previously introduced in the past, but not from one recently introduced.

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