Glycogen synthase kinase-3β inhibition induces nuclear factor-κB-mediated apoptosis in pediatric acute lymphocyte leukemia cells

BACKGROUND: Molecular therapies that target genetic abnormalities in leukemic cells and their affected signaling pathways have been emerging in pediatric acute lymphoblastic leukemia (ALL). Glycogen synthase kinase-3β (GSK-3β) has recently been found to positively regulate the activity of nuclear fa...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Yanni, Gu, Xiaoyan, Li, Ruiyan, Luo, Qing, Xu, Youhua
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002327/
https://www.ncbi.nlm.nih.gov/pubmed/21110852
http://dx.doi.org/10.1186/1756-9966-29-154

Ejemplares similares

Ejemplares similares