Cargando…

Can herpes simplex virus type 2 suppression slow HIV disease progression: a study protocol for the VALacyclovir In Delaying Antiretroviral Treatment Entry (VALIDATE) trial

BACKGROUND: Although highly active antiretroviral therapy (HAART) has dramatically decreased HIV-related morbidity and mortality, the associated costs, toxicities, and resistance risks make the potential delay of HAART initiation an attractive goal. Suppression of herpes simplex virus type 2 (HSV-2)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tan, Darrell HS, Raboud, Janet M, Kaul, Rupert, Grinsztejn, Beatriz, Cahn, Pedro, Walmsley, Sharon L
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002348/ https://www.ncbi.nlm.nih.gov/pubmed/21106086 http://dx.doi.org/10.1186/1745-6215-11-113

Ejemplares similares

Antiretroviral therapy is not associated with reduced herpes simplex virus shedding in HIV coinfected adults: an observational cohort study
por: Tan, Darrell H S, et al.
Publicado: (2014)

Effect of Intercurrent Infections and Vaccinations on Immune and Inflammatory Biomarkers Among Human Immunodeficiency Virus-Infected Adults on Suppressive Antiretroviral Therapy
por: Tan, Darrell H. S., et al.
Publicado: (2015)

Effects of Valacyclovir on Markers of Disease Progression in Postpartum Women Co-Infected with HIV-1 and Herpes Simplex Virus-2
por: Roxby, Alison C., et al.
Publicado: (2012)

Herpes simplex virus type 2 and HIV disease progression: a systematic review of observational studies
por: Tan, Darrell Hoi-San, et al.
Publicado: (2013)

Efficacy of valacyclovir and famciclovir in herpes zoster: A comparative study
por: Bist, Ankita, et al.
Publicado: (2020)

Genital Herpes Simplex Virus Type 2 Suppression With Valacyclovir Is Not Associated With Changes in Nugent Score or Absolute Abundance of Key Vaginal Bacteria
por: Babu, Tara M, et al.
Publicado: (2023)

Oral Valacyclovir Treatment of Herpes Zoster Ophthalmicus-Induced Optic Neuritis
por: Hunt, Christina M, et al.
Publicado: (2021)

Inflammatory biomarker levels over 48 weeks with dual vs triple lopinavir/ritonavir-based therapy: Substudy of a randomized trial
por: Tan, Darrell H. S., et al.
Publicado: (2019)

Exploiting Herpes Simplex Virus Entry for Novel Therapeutics
por: Hadigal, Satvik, et al.
Publicado: (2013)

Herpes Simplex Virus Cell Entry Mechanisms: An Update
por: Madavaraju, Krishnaraju, et al.
Publicado: (2021)

Effect of valaciclovir on CD4 count decline in untreated HIV: an international randomized controlled trial
por: Tan, Darrell H S, et al.
Publicado: (2019)

Herpes Simplex Virus 1 Targets the Murine Olfactory Neuroepithelium for Host Entry
por: Shivkumar, Maitreyi, et al.
Publicado: (2013)

Long-term valacyclovir treatment and immune modulation for Herpes-associated erythema multiforme
por: Staikuniene, Jurate, et al.
Publicado: (2015)

Structure-Based Mutations in the Herpes Simplex Virus 1 Glycoprotein B Ectodomain Arm Impart a Slow-Entry Phenotype
por: Fan, Qing, et al.
Publicado: (2017)

Once Daily Valacyclovir for Reducing Viral Shedding in Subjects Newly Diagnosed with Genital Herpes
por: Martens, Mark G., et al.
Publicado: (2009)

Suppressive valacyclovir therapy to reduce genital herpes transmission: Good public health policy?
por: Bonnar, Paul E
Publicado: (2009)

Immunological Signaling During Herpes Simplex Virus-2 and Cytomegalovirus Vaginal Shedding After Initiation of Antiretroviral Treatment
por: Nason, Martha C., et al.
Publicado: (2016)

A novel role for phagocytosis-like uptake in herpes simplex virus entry
por: Clement, Christian, et al.
Publicado: (2006)

Herpes Simplex Virus Glycoprotein C Regulates Low-pH Entry
por: Komala Sari, Tri, et al.
Publicado: (2020)

Progressive Hypertrophic Genital Herpes in an HIV-Infected Woman despite Immune Recovery on Antiretroviral Therapy
por: Yudin, Mark H., et al.
Publicado: (2008)

Harringtonine Inhibits Herpes Simplex Virus Type 1 Infection by Reducing Herpes Virus Entry Mediator Expression
por: Liu, Ye, et al.
Publicado: (2021)

Clinical study in genital herpes: natural Gene-Eden-VIR/Novirin versus acyclovir, valacyclovir, and famciclovir
por: Polansky, Hanan, et al.
Publicado: (2016)

Entry of Oncolytic Herpes Simplex Virus into Human Squamous Cell Carcinoma Cells by Ultrasound
por: Okunaga, Shusuke, et al.
Publicado: (2015)

Valacyclovir in the treatment of acute retinal necrosis
por: Taylor, Simon RJ, et al.
Publicado: (2012)

Valacyclovir-Induced Thrombotic Thrombocytopenic Purpura
por: Bukhari, Sumera, et al.
Publicado: (2020)

Entry Pathways of Herpes Simplex Virus Type 1 into Human Keratinocytes Are Dynamin- and Cholesterol-Dependent
por: Rahn, Elena, et al.
Publicado: (2011)

Latency Entry of Herpes Simplex Virus 1 Is Determined by the Interaction of Its Genome with the Nuclear Environment
por: Maroui, Mohamed Ali, et al.
Publicado: (2016)

Herpes Simplex Virus 1 Entry Glycoproteins Form Complexes before and during Membrane Fusion
por: Pataki, Zemplen, et al.
Publicado: (2022)

Immunological control of herpes simplex virus infections
por: Egan, Kevin P., et al.
Publicado: (2013)

Comparison of atazanavir/ritonavir and darunavir/ritonavir based antiretroviral therapy for antiretroviral naïve patients
por: Antoniou, Tony, et al.
Publicado: (2017)

Valacyclovir associated neurotoxicity in a patient on dialysis
por: Singh, N. P., et al.
Publicado: (2014)

Herpesvirus Entry Mediator on Radiation-Resistant Cell Lineages Promotes Ocular Herpes Simplex Virus 1 Pathogenesis in an Entry-Independent Manner
por: Edwards, Rebecca G., et al.
Publicado: (2015)

Tin Oxide Nanowires Suppress Herpes Simplex Virus-1 Entry and Cell-to-Cell Membrane Fusion
por: Trigilio, James, et al.
Publicado: (2012)

Herpesvirus Entry Mediator Binding Partners Mediate Immunopathogenesis of Ocular Herpes Simplex Virus 1 Infection
por: Park, Seo J., et al.
Publicado: (2020)

Herpes Simplex and Pseudorabies Viruses
por: Hierholzer, Walter J.
Publicado: (1970)

Treatment of Herpes Simplex Encephalitis
por: Illis, L. S., et al.
Publicado: (1972)

Fulminating herpes simplex hepatitis
por: Ahmed, Raheel, et al.
Publicado: (2022)

The interaction of Herpes Simplex Virus with murine lymphocytes. I. Mitogenic properties of herpes simplex virus
Publicado: (1977)

A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis
por: Uyar, Olus, et al.
Publicado: (2021)

Quality Assessment of Process Measures in Antimicrobial Stewardship: Concordance of Valacyclovir Indication and Automatic Prospective Approval in Computerized Provider Order Entry
por: Lee, Tiffany, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_l63vj2ktpmuc8o43e5qvagth4t