Defining a minimal clinically important difference for endometriosis-associated pelvic pain measured on a visual analog scale: analyses of two placebo-controlled, randomized trials

BACKGROUND: When comparing active treatments, a non-inferiority (or one-sided equivalence) study design is often used. This design requires the definition of a non-inferiority margin, the threshold value of clinical relevance. In recent studies, a non-inferiority margin of 15 mm has been used for th...

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Detalles Bibliográficos
Autores principales: Gerlinger, Christoph, Schumacher, Ulrike, Faustmann, Thomas, Colligs, Antje, Schmitz, Heinz, Seitz, Christian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002916/
https://www.ncbi.nlm.nih.gov/pubmed/21106059
http://dx.doi.org/10.1186/1477-7525-8-138

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