Epigenetic silencing of MAL, a putative tumor suppressor gene, can contribute to human epithelium cell carcinoma

BACKGROUND: To identify new and useful candidate biomarkers in head and neck squamous cell carcinoma (HNSCC), we performed a genome-wide survey and found that Myelin and lymphocyte-associated protein (MAL) was a gene that was markedly down-regulated in HNSCC. Hence, we investigated the mechanism of...

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Detalles Bibliográficos
Autores principales: Cao, Wei, Zhang, Zhi-yuan, Xu, Qin, Sun, Qiang, Yan, Ming, Zhang, Jun, Zhang, Ping, Han, Ze-guang, Chen, Wan-tao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002926/
https://www.ncbi.nlm.nih.gov/pubmed/21092172
http://dx.doi.org/10.1186/1476-4598-9-296

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