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Expression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells

BACKGROUND: Glucocorticoids (GCs) cause apoptosis and cell cycle arrest in lymphoid cells and constitute a central component in the therapy of lymphoid malignancies, most notably childhood acute lymphoblastic leukemia (ALL). PFKFB2 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-2), a kinase co...

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Detalles Bibliográficos
Autores principales:	Carlet, Michela, Janjetovic, Kristina, Rainer, Johannes, Schmidt, Stefan, Panzer-Grümayer, Renate, Mann, Georg, Prelog, Martina, Meister, Bernhard, Ploner, Christian, Kofler, Reinhard
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002928/ https://www.ncbi.nlm.nih.gov/pubmed/21092265 http://dx.doi.org/10.1186/1471-2407-10-638

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