A Porcine Adenovirus with Low Human Seroprevalence Is a Promising Alternative Vaccine Vector to Human Adenovirus 5 in an H5N1 Virus Disease Model

Human adenovirus 5 (AdHu5) vectors are robust vaccine platforms however the presence of naturally-acquired neutralizing antibodies may reduce vector efficacy and potential for re-administration. This study evaluates immune responses and protection following vaccination with a replication-incompetent...

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Detalles Bibliográficos
Autores principales: Patel, Ami, Tikoo, Suresh, Kobinger, Gary
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002947/
https://www.ncbi.nlm.nih.gov/pubmed/21179494
http://dx.doi.org/10.1371/journal.pone.0015301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002947/
https://www.ncbi.nlm.nih.gov/pubmed/21179494
http://dx.doi.org/10.1371/journal.pone.0015301

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