Targeting the IL-6 Dependent Phenotype Can Identify Novel Therapies for Cholangiocarcinoma

BACKGROUND: The need for new therapies for cholangiocarcinoma is highlighted by their poor prognosis and refractoriness to chemotherapy. Increased production of Interleukin-6 promotes cholangiocarcinoma growth and contributes to chemoresistance by activating cell survival mechanisms. We sought to id...

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Detalles Bibliográficos
Autores principales: Braconi, Chiara, Swenson, Erica, Kogure, Takayuki, Huang, Nianyuan, Patel, Tushar
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002961/
https://www.ncbi.nlm.nih.gov/pubmed/21179572
http://dx.doi.org/10.1371/journal.pone.0015195

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