Cargando…

Dimeric 2G12 as a Potent Protection against HIV-1

We previously showed that broadly neutralizing anti-HIV-1 antibody 2G12 (human IgG1) naturally forms dimers that are more potent than monomeric 2G12 in in vitro neutralization of various strains of HIV-1. In this study, we have investigated the protective effects of monomeric versus dimeric 2G12 aga...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Xin M., Lei, Margarida Y. Y., Feidi, Rana A., West, Anthony P., Balazs, Alejandro Benjamin, Bjorkman, Pamela J., Yang, Lili, Baltimore, David
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002980/
https://www.ncbi.nlm.nih.gov/pubmed/21187894
http://dx.doi.org/10.1371/journal.ppat.1001225