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Dimeric 2G12 as a Potent Protection against HIV-1

We previously showed that broadly neutralizing anti-HIV-1 antibody 2G12 (human IgG1) naturally forms dimers that are more potent than monomeric 2G12 in in vitro neutralization of various strains of HIV-1. In this study, we have investigated the protective effects of monomeric versus dimeric 2G12 aga...

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Detalles Bibliográficos
Autores principales:	Luo, Xin M., Lei, Margarida Y. Y., Feidi, Rana A., West, Anthony P., Balazs, Alejandro Benjamin, Bjorkman, Pamela J., Yang, Lili, Baltimore, David
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002980/ https://www.ncbi.nlm.nih.gov/pubmed/21187894 http://dx.doi.org/10.1371/journal.ppat.1001225

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