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Combining Network Modeling and Gene Expression Microarray Analysis to Explore the Dynamics of Th1 and Th2 Cell Regulation
Two T helper (Th) cell subsets, namely Th1 and Th2 cells, play an important role in inflammatory diseases. The two subsets are thought to counter-regulate each other, and alterations in their balance result in different diseases. This paradigm has been challenged by recent clinical and experimental...
Autores principales: | Pedicini, Marco, Barrenäs, Fredrik, Clancy, Trevor, Castiglione, Filippo, Hovig, Eivind, Kanduri, Kartiek, Santoni, Daniele, Benson, Mikael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002992/ https://www.ncbi.nlm.nih.gov/pubmed/21187905 http://dx.doi.org/10.1371/journal.pcbi.1001032 |
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