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The Evolutionary Analysis of Emerging Low Frequency HIV-1 CXCR4 Using Variants through Time—An Ultra-Deep Approach

Large-scale parallel pyrosequencing produces unprecedented quantities of sequence data. However, when generated from viral populations current mapping software is inadequate for dealing with the high levels of variation present, resulting in the potential for biased data loss. In order to apply the...

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Detalles Bibliográficos
Autores principales:	Archer, John, Rambaut, Andrew, Taillon, Bruce E., Harrigan, P. Richard, Lewis, Marilyn, Robertson, David L.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002995/ https://www.ncbi.nlm.nih.gov/pubmed/21187908 http://dx.doi.org/10.1371/journal.pcbi.1001022

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