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Distinct Functions for the Drosophila piRNA Pathway in Genome Maintenance and Telomere Protection

Transposons and other selfish DNA elements can be found in all phyla, and mobilization of these elements can compromise genome integrity. The piRNA (PIWI-interacting RNA) pathway silences transposons in the germline, but it is unclear if this pathway has additional functions during development. Here...

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Detalles Bibliográficos
Autores principales: Khurana, Jaspreet S., Xu, Jia, Weng, Zhiping, Theurkauf, William E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003142/
https://www.ncbi.nlm.nih.gov/pubmed/21179579
http://dx.doi.org/10.1371/journal.pgen.1001246