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Optimization of Luminescent Assay for Screening of Cyclin-Dependent Kinase 2 Inhibitors
Cyclin-dependent kinases are most extensively studied targets for cancer chemotherapy since the tumor cells exhibit false checkpoints and can proliferate even if the genome is compromised. Cyclin-dependent kinases ensure the tight regulation of the cell cycle execution by mediating phosphorylation o...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003159/ https://www.ncbi.nlm.nih.gov/pubmed/21188035 http://dx.doi.org/10.4103/0250-474X.70472 |