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Optimization of Luminescent Assay for Screening of Cyclin-Dependent Kinase 2 Inhibitors
Cyclin-dependent kinases are most extensively studied targets for cancer chemotherapy since the tumor cells exhibit false checkpoints and can proliferate even if the genome is compromised. Cyclin-dependent kinases ensure the tight regulation of the cell cycle execution by mediating phosphorylation o...
Autores principales: | Suthar, M. P., Patel, M. M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003159/ https://www.ncbi.nlm.nih.gov/pubmed/21188035 http://dx.doi.org/10.4103/0250-474X.70472 |
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