Legionella pneumophila induces cathepsin B-dependent necrotic cell death with releasing high mobility group box1 in macrophages

BACKGROUND: Legionella pneumophila (LPN) can cause a lethal infectious disease with a marked inflammatory response in humans. However, the mechanism of this severe inflammation remains poorly understood. Since necrosis is known to induce inflammation, we investigated whether LPN induces necrosis in...

Descripción completa

Detalles Bibliográficos
Autores principales: Morinaga, Yoshitomo, Yanagihara, Katsunori, Nakamura, Shigeki, Hasegawa, Hiroo, Seki, Masafumi, Izumikawa, Koichi, Kakeya, Hiroshi, Yamamoto, Yoshihiro, Yamada, Yasuaki, Kohno, Shigeru, Kamihira, Shimeru
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003236/
https://www.ncbi.nlm.nih.gov/pubmed/21092200
http://dx.doi.org/10.1186/1465-9921-11-158

Ejemplares similares

Ejemplares similares