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Genetic constraints for thermal coadaptation in Drosophila subobscura

BACKGROUND: Behaviour has been traditionally viewed as a driver of subsequent evolution because behavioural adjustments expose organisms to novel environments, which may result in a correlated evolution on other traits. In Drosophila subobscura, thermal preference and heat tolerance are linked to ch...

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Autores principales: Dolgova, Olga, Rego, Carla, Calabria, Gemma, Balanyà, Joan, Pascual, Marta, Rezende, Enrico L, Santos, Mauro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003277/
https://www.ncbi.nlm.nih.gov/pubmed/21108788
http://dx.doi.org/10.1186/1471-2148-10-363
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author Dolgova, Olga
Rego, Carla
Calabria, Gemma
Balanyà, Joan
Pascual, Marta
Rezende, Enrico L
Santos, Mauro
author_facet Dolgova, Olga
Rego, Carla
Calabria, Gemma
Balanyà, Joan
Pascual, Marta
Rezende, Enrico L
Santos, Mauro
author_sort Dolgova, Olga
collection PubMed
description BACKGROUND: Behaviour has been traditionally viewed as a driver of subsequent evolution because behavioural adjustments expose organisms to novel environments, which may result in a correlated evolution on other traits. In Drosophila subobscura, thermal preference and heat tolerance are linked to chromosomal inversion polymorphisms that show parallel latitudinal clines worldwide, such that "cold-climate" ("warm-climate") chromosome arrangements collectively favour a coherent response to colder (warmer) settings as flies carrying them prefer colder (warmer) conditions and have lower (higher) knock out temperatures. Yet, it is not clear whether a genetic correlation between thermal preference and heat tolerance can partially underlie such response. RESULTS: We have analyzed the genetic basis of thermal preference and heat tolerance using isochromosomal lines in D. subobscura. Chromosome arrangements on the O chromosome were known to have a biometrical effect on thermal preference in a laboratory temperature gradient, and also harbour several genes involved in the heat shock response; in particular, the genes Hsp68 and Hsp70. Our results corroborate that arrangements on chromosome O affect adult thermal preference in a laboratory temperature gradient, with cold-climate O(st )carriers displaying a lower thermal preference than their warm-climate O(3+4 )and O(3+4+8 )counterparts. However, these chromosome arrangements did not have any effect on adult heat tolerance and, hence, we putatively discard a genetic covariance between both traits arising from linkage disequilibrium between genes affecting thermal preference and candidate genes for heat shock resistance. Nonetheless, a possible association of juvenile thermal preference and heat resistance warrants further analysis. CONCLUSIONS: Thermal preference and heat tolerance in the isochromosomal lines of D. subobscura appear to be genetically independent, which might potentially prevent a coherent response of behaviour and physiology (i.e., coadaptation) to thermal selection. If this pattern is general to all chromosomes, then any correlation between thermal preference and heat resistance across latitudinal gradients would likely reflect a pattern of correlated selection rather than genetic correlation.
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spelling pubmed-30032772011-01-06 Genetic constraints for thermal coadaptation in Drosophila subobscura Dolgova, Olga Rego, Carla Calabria, Gemma Balanyà, Joan Pascual, Marta Rezende, Enrico L Santos, Mauro BMC Evol Biol Research Article BACKGROUND: Behaviour has been traditionally viewed as a driver of subsequent evolution because behavioural adjustments expose organisms to novel environments, which may result in a correlated evolution on other traits. In Drosophila subobscura, thermal preference and heat tolerance are linked to chromosomal inversion polymorphisms that show parallel latitudinal clines worldwide, such that "cold-climate" ("warm-climate") chromosome arrangements collectively favour a coherent response to colder (warmer) settings as flies carrying them prefer colder (warmer) conditions and have lower (higher) knock out temperatures. Yet, it is not clear whether a genetic correlation between thermal preference and heat tolerance can partially underlie such response. RESULTS: We have analyzed the genetic basis of thermal preference and heat tolerance using isochromosomal lines in D. subobscura. Chromosome arrangements on the O chromosome were known to have a biometrical effect on thermal preference in a laboratory temperature gradient, and also harbour several genes involved in the heat shock response; in particular, the genes Hsp68 and Hsp70. Our results corroborate that arrangements on chromosome O affect adult thermal preference in a laboratory temperature gradient, with cold-climate O(st )carriers displaying a lower thermal preference than their warm-climate O(3+4 )and O(3+4+8 )counterparts. However, these chromosome arrangements did not have any effect on adult heat tolerance and, hence, we putatively discard a genetic covariance between both traits arising from linkage disequilibrium between genes affecting thermal preference and candidate genes for heat shock resistance. Nonetheless, a possible association of juvenile thermal preference and heat resistance warrants further analysis. CONCLUSIONS: Thermal preference and heat tolerance in the isochromosomal lines of D. subobscura appear to be genetically independent, which might potentially prevent a coherent response of behaviour and physiology (i.e., coadaptation) to thermal selection. If this pattern is general to all chromosomes, then any correlation between thermal preference and heat resistance across latitudinal gradients would likely reflect a pattern of correlated selection rather than genetic correlation. BioMed Central 2010-11-25 /pmc/articles/PMC3003277/ /pubmed/21108788 http://dx.doi.org/10.1186/1471-2148-10-363 Text en Copyright ©2010 Dolgova et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (<url>http://creativecommons.org/licenses/by/2.0</url>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Dolgova, Olga
Rego, Carla
Calabria, Gemma
Balanyà, Joan
Pascual, Marta
Rezende, Enrico L
Santos, Mauro
Genetic constraints for thermal coadaptation in Drosophila subobscura
title Genetic constraints for thermal coadaptation in Drosophila subobscura
title_full Genetic constraints for thermal coadaptation in Drosophila subobscura
title_fullStr Genetic constraints for thermal coadaptation in Drosophila subobscura
title_full_unstemmed Genetic constraints for thermal coadaptation in Drosophila subobscura
title_short Genetic constraints for thermal coadaptation in Drosophila subobscura
title_sort genetic constraints for thermal coadaptation in drosophila subobscura
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003277/
https://www.ncbi.nlm.nih.gov/pubmed/21108788
http://dx.doi.org/10.1186/1471-2148-10-363
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