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Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

Neutrophils release decondensed chromatin termed neutrophil extracellular traps (NETs) to trap and kill pathogens extracellularly. Reactive oxygen species are required to initiate NET formation but the downstream molecular mechanism is unknown. We show that upon activation, neutrophil elastase (NE)...

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Detalles Bibliográficos
Autores principales:	Papayannopoulos, Venizelos, Metzler, Kathleen D., Hakkim, Abdul, Zychlinsky, Arturo
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003309/ https://www.ncbi.nlm.nih.gov/pubmed/20974816 http://dx.doi.org/10.1083/jcb.201006052

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