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Quality control for unfolded proteins at the plasma membrane
Cellular protein homeostasis profoundly depends on the disposal of terminally damaged polypeptides. To demonstrate the operation and elucidate the molecular basis of quality control of conformationally impaired plasma membrane (PM) proteins, we constructed CD4 chimeras containing the wild type or a...
Autores principales: | Apaja, Pirjo M., Xu, Haijin, Lukacs, Gergely L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003321/ https://www.ncbi.nlm.nih.gov/pubmed/20974815 http://dx.doi.org/10.1083/jcb.201006012 |
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