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Functional Complementation and Genetic Deletion Studies of KirBac Channels: ACTIVATORY MUTATIONS HIGHLIGHT GATING-SENSITIVE DOMAINS

The superfamily of prokaryotic inwardly rectifying (KirBac) potassium channels is homologous to mammalian Kir channels. However, relatively little is known about their regulation or about their physiological role in vivo. In this study, we have used random mutagenesis and genetic complementation in...

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Detalles Bibliográficos
Autores principales:	Paynter, Jennifer J., Andres-Enguix, Isabelle, Fowler, Philip W., Tottey, Stephen, Cheng, Wayland, Enkvetchakul, Decha, Bavro, Vassiliy N., Kusakabe, Yoshio, Sansom, Mark S. P., Robinson, Nigel J., Nichols, Colin G., Tucker, Stephen J.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2010
Materias:	Membrane Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003375/ https://www.ncbi.nlm.nih.gov/pubmed/20876570 http://dx.doi.org/10.1074/jbc.M110.175687

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