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Extended Binding Site on Fibronectin for the Functional Upstream Domain of Protein F1 of Streptococcus pyogenes

The 49-residue functional upstream domain (FUD) of Streptococcus pyogenes F1 adhesin interacts with fibronectin (FN) in a heretofore unknown manner that prevents assembly of a FN matrix. Biotinylated FUD (b-FUD) bound to adsorbed FN or its recombinant N-terminal 70-kDa fibrin- and gelatin-binding fr...

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Detalles Bibliográficos
Autores principales: Maurer, Lisa M., Tomasini-Johansson, Bianca R., Ma, Wenjiang, Annis, Douglas S., Eickstaedt, Nathan L., Ensenberger, Martin G., Satyshur, Kenneth A., Mosher, Deane F.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003407/
https://www.ncbi.nlm.nih.gov/pubmed/20947497
http://dx.doi.org/10.1074/jbc.M110.153692