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Active immunization to tumor necrosis factor-α is effective in treating chronic established inflammatory disease: a long-term study in a transgenic model of arthritis

INTRODUCTION: Passive blockade of tumor necrosis factor-alpha (TNF-α) has demonstrated high therapeutic efficiency in chronic inflammatory diseases, such as rheumatoid arthritis, although some concerns remain such as occurrence of resistance and high cost. These limitations prompted investigations o...

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Detalles Bibliográficos
Autores principales:	Delavallée, Laure, Semerano, Luca, Assier, Eric, Vogel, Géraldine, Vuagniaux, Grégoire, Laborie, Marion, Zagury, Daniel, Bessis, Natacha, Boissier, Marie-Christophe
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003505/ https://www.ncbi.nlm.nih.gov/pubmed/20030816 http://dx.doi.org/10.1186/ar2897

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