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Immunocytokines: the long awaited therapeutic magic bullet in rheumatoid arthritis?

Modulatory cytokines such as IL-4 and IL-10 looked promising biologicals, but suffered from poor exposure at the inflamed joints when administered via the patient-friendly subcutaneous route. Immunocytokines have now been engineered with tissue targeting potential and are a possible solution to this...

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Detalles Bibliográficos
Autores principales: van de Loo, Fons A, van den Berg, Wim B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003506/
https://www.ncbi.nlm.nih.gov/pubmed/19903325
http://dx.doi.org/10.1186/ar2835

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