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Immunocytokines: the long awaited therapeutic magic bullet in rheumatoid arthritis?
Modulatory cytokines such as IL-4 and IL-10 looked promising biologicals, but suffered from poor exposure at the inflamed joints when administered via the patient-friendly subcutaneous route. Immunocytokines have now been engineered with tissue targeting potential and are a possible solution to this...
Autores principales: | van de Loo, Fons A, van den Berg, Wim B |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003506/ https://www.ncbi.nlm.nih.gov/pubmed/19903325 http://dx.doi.org/10.1186/ar2835 |
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