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Genetic variability and natural selection at the ligand domain of the Duffy binding protein in brazilian Plasmodium vivax populations

BACKGROUND: Plasmodium vivax malaria is a major public health challenge in Latin America, Asia and Oceania, with 130-435 million clinical cases per year worldwide. Invasion of host blood cells by P. vivax mainly depends on a type I membrane protein called Duffy binding protein (PvDBP). The erythrocy...

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Detalles Bibliográficos
Autores principales: Sousa, Taís N, Tarazona-Santos, Eduardo M, Wilson, Daniel J, Madureira, Ana P, Falcão, Paula RK, Fontes, Cor JF, Gil, Luiz HS, Ferreira, Marcelo U, Carvalho, Luzia H, Brito, Cristiana FA
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003673/
https://www.ncbi.nlm.nih.gov/pubmed/21092207
http://dx.doi.org/10.1186/1475-2875-9-334