β-Amyloid 1-42 Oligomers Impair Function of Human Embryonic Stem Cell-Derived Forebrain Cholinergic Neurons

Cognitive impairment in Alzheimer's disease (AD) patients is associated with a decline in the levels of growth factors, impairment of axonal transport and marked degeneration of basal forebrain cholinergic neurons (BFCNs). Neurogenesis persists in the adult human brain, and the stimulation of r...

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Detalles Bibliográficos
Autores principales: Wicklund, Linn, Leão, Richardson N., Strömberg, Anne-Marie, Mousavi, Malahat, Hovatta, Outi, Nordberg, Agneta, Marutle, Amelia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003688/
https://www.ncbi.nlm.nih.gov/pubmed/21179413
http://dx.doi.org/10.1371/journal.pone.0015600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003688/
https://www.ncbi.nlm.nih.gov/pubmed/21179413
http://dx.doi.org/10.1371/journal.pone.0015600

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