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Germline mutations in CDH1 are infrequent in women with early-onset or familial lobular breast cancers

BACKGROUND: Germline mutations in CDH1 are associated with hereditary diffuse gastric cancer; lobular breast cancer also occurs excessively in families with such condition. METHOD: To determine if CDH1 is a susceptibility gene for lobular breast cancer in women without a family history of diffuse ga...

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Detalles Bibliográficos
Autores principales: Schrader, K A, Masciari, S, Boyd, N, Salamanca, C, Senz, J, Saunders, D N, Yorida, E, Maines-Bandiera, S, Kaurah, P, Tung, N, Robson, M E, Ryan, P D, Olopade, O I, Domchek, S M, Ford, J, Isaacs, C, Brown, P, Balmana, J, Razzak, A R, Miron, P, Coffey, K, Terry, M B, John, E M, Andrulis, I L, Knight, J A, O'Malley, F P, Daly, M, Bender, P, Moore, R, Southey, M C, Hopper, J L, Garber, J E, Huntsman, D G
Formato: Texto
Lenguaje:English
Publicado: BMJ Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003879/
https://www.ncbi.nlm.nih.gov/pubmed/20921021
http://dx.doi.org/10.1136/jmg.2010.079814