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Neurokinin-1 Receptor Antagonist Treatment in Polymicrobial Sepsis: Molecular Insights

Neurokinin-1 receptor blocking has been shown to be beneficial against lung injury in polymicrobial sepsis. In this paper, we evaluated the possible mediators and the mechanism involved. Mice were subjected to cecal ligation and puncture (CLP-) induced sepsis or sham surgery. Vehicle or SR140333 [1 ...

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Detalles Bibliográficos
Autores principales: Hegde, Akhil, Koh, Yung-Hua, Moochhala, Shabbir M., Bhatia, Madhav
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003979/
https://www.ncbi.nlm.nih.gov/pubmed/21188216
http://dx.doi.org/10.4061/2010/601098

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